What symptom is commonly associated with necator americanus infection?

Necator americanus, commonly known as the New World hookworm, is associated with several clinical manifestations, most notably iron deficiency anemia. This condition arises due to the parasite's feeding behavior; adult hookworms attach to the intestinal mucosa and consume blood, leading to significant blood loss over time. As the infection progresses, the cumulative loss can result in a decrease in hemoglobin and red blood cells, ultimately manifesting as anemia.

In addition to anemia, a hookworm infection can lead to various gastrointestinal symptoms, but the hallmark symptom linked specifically to the chronic infection with Necator americanus is indeed iron deficiency anemia. The other symptoms, while they may occur in association with hookworm infections or other gastrointestinal diseases, do not capture the primary effect of this specific parasite on the host's health as accurately as anemia does.