In which patient group is caution advised when using Ivermectin?

When using Ivermectin, caution is particularly advised for pediatric patients under 15 kg due to the risk of increased sensitivity to the drug and the potential for adverse effects. This weight category typically aligns with younger children who may not have fully matured metabolic pathways, making them more vulnerable to the effects of medications. The dosing must be carefully considered to ensure safety and efficacy, as children can experience different pharmacokinetic and pharmacodynamic responses compared to adults.

In contrast, while pregnant women, patients with heart conditions, and geriatric patients do require careful consideration regarding medication use, the specific caution around dosing and the potential for severe reactions is most pronounced in very young patients. Additionally, there are established guidelines for the use of Ivermectin in these other groups, which may include adjusting dosages or monitoring for specific side effects, but the pediatric population under 15 kg stands out as requiring considerable caution.